IGF2R-Targeted Alpha Therapy of Osteosarcoma Enabled by Conjugated [ 225 Ac]Ac-Macropa-PEG 4 -IF3
Articles > Article · 2026
Authors: Syed Qaiser Shah, Ralph Santos-Oliveira, Derya İLEM ÖZDEMİR, Madeeha Shabnam
Bioconjugate Chemistry, International, WoS, 2026, vol 37, pp 1025-1034
DOI: 10.1021/acs.bioconjchem.6c00125
Summary
-IF3 is a translational orphan alpha therapeutic for osteosarcoma with excellent radiochemical stability and potency and low off-target toxicity.