Comorbidities and their impact on chronic obstructive pulmonary disease
Makaleler > Tam Makale · 2016
Yazarlar: Neşe DURSUNOĞLU, Nurdan KÖKTÜRK, Ayşe BAHA, Ahmet Kaya BİLGE, Şermin BÖREKÇİ, Fatma ÇİFTÇİ, Makbule GEZMEN KARADAĞ, Ebru ÇALIK KÜTÜKÇÜ, Ayşın NOYAN, Mehmet POLATLI, Zeynep Pınar ÖNEN, Sevinç SARINÇ, Sema UMUT, Esra UZASLAN, Ayşe KUBAT ÜZÜM, Öznur AKKOCA YILDIZ
Tuberkuloz ve Toraks, Uluslararası, Scopus, 2016, cilt 64, ss 289-298
DOI: 10.5578/tt.2245
Özet
Chronic obstructive pulmonary disease (COPD) is a complex disease that is associated with devastating outcomes resulting from lung involvement and several comorbidities. Comorbidities could impact on symptomology, quality of life, the complications, the management, economic burden and the mortality of the disease. The importance of comorbidities originates from their impact on the outcome of COPD. The most frequent comorbidities in COPD are cardiovascular, endocrinological, musculoskeletal, phycological disorders and lung cancer. Almost 50% of the COPD patients have 3 or more comorbidities. The recent Global Initiative of Obstructive Lung Disease (GOLD) Guideline suggested proactive search and the treatment of the comorbidities. However, there is no certain evidence demonstrating that active treatment of comorbidities improve the outcomes of COPD. However, it is well known that several comorbidities such as cardiovascular disease and lung cancer have greater impact on mortality caused by COPD. Several studies have shown that Charlson Comorbidity index or more recenty COPD Specific Comorbidity Index (COTE) has been found to be related with mortality of COPD. This concise review intended to summarize the most frequent comorbidities in association with their impact on COPD.