Contraction induced by (-)-tartaric acid on rat isolated gastric fundus and its inhibition with indomethacin

Articles > Article · 1985

Authors: Levent Tug̀rul, Asli Özer

Journal of Pharmacy and Pharmacology, International, 1985, vol 37, pp 583-584

DOI: 10.1111/j.2042-7158.1985.tb03075.x

Summary

Tartaric acid-evoked contractions of the rat isolated fundus could not be antagonized by atropine sulphate or methysergide hydrogen maleate, but were partially reduced by mepyramine hydrochloride. The contractions were prevented by indomethacin (25 micrograms ml-1) although the tissue remained sensitive to PGE2.

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