Susceptibility of extended-spectrum beta-lactamase-producing Escherichia coli urine isolates to fosfomycin, ciprofloxacin, amikacin and trimethoprim-sulfamethoxazole
Articles > Article · 2008
Authors: Hüsnü PULLUKÇU, Sohret AYDEMİR, Meltem TAŞBAKAN, Fatma Feriha ÇİLLİ, Alper TÜNGER, Sercan ULUSOY
TURKISH JOURNAL OF MEDICAL SCIENCES, Journal Indexed in SCI Expanded, International, 2008, vol 38, pp 175-180
Summary
Aim: Urinary tract infections (UTIs) caused in particular by extended-spectrum beta-lactamase (ESBL)producing Escherichia coli strains are related with high morbidity and mortality, and treatment is quite difficult. These infections generally are treated by carbapenems, and their costs are high. We aimed in this study to investigate the susceptibilities of ESBL-producing E. coli strains isolated from urine cultures to fosfomycin, ciprofloxacin, amikacin and trimethoprim-sulfamethoxazole and to determine the general resistance profile in our region of these strains isolated from UTIs.