Association between the eNOS (Glu298Asp) and the RAS genes polymorphisms and premature coronary artery disease in a Turkish population
Makaleler > Tam Makale · 2004
Yazarlar: Afig BERDELİ, C Sekuri, FS Cam, E Ercan, A Sagcan, I Tengiz, E Eser, M Akin
Clinica Chimica Acta, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2004, cilt 351, ss 87-94
DOI: 10.1016/j.cccn.2004.08.015
Özet
Background: The renin-angiotensin system (RAS) and endothelial nitric oxide (NO) affect the pathogenesis of atherosclerosis and prognosis of coronary artery disease (CAD). Previous epidemiologic data suggested that genetic factors are more likely to affect young rather than old people. Our objective was to investigate the association between the polymorphisms of eNOS (Glu298Asp) and the RAS genes and premature CAD in a Turkish population.