Use of Two Sensitive and Specific Immunoblot Markers, Em70 and Em90, for Diagnosis of Alveolar Echinococcosis

Articles > Article ยท 2004

Authors: Metin KORKMAZ, T Inceboz, F Celebi, A Babaoglu, A Uner

Journal of Clinical Microbiology, Journal Indexed in SCI Expanded, International, WoS, 2004, vol 42, pp 3350-3352

DOI: 10.1128/jcm.42.7.3350-3352.2004

Summary

Antibodies against Echinococcus multilocularis metacestodes were screened by immunoblotting sera from patients with alveolar echinococcosis (n = 39), cystic echinococcosis (n = 109), or other parasitic infections (n = 66) and healthy individuals (n = 32). Two antigens, approximately 70 and 90 kDa, are found to be valuable for confirmatory diagnosis, with a sensitivity and specificity of 100 and 99.51%, respectively.

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