Subclinical Neurological Abnormalities in Children With Celiac Disease Receiving a Gluten‐free Diet
Makaleler > Tam Makale · 2007
Yazarlar: D. CAKIR, A. TOSUN, Meltem POLAT, Neşe ÇELEBİSOY, SARENUR GÖKBEN, S. AYDOGDU, R. V. YAGCI, Hasan TEKGÜL
Journal of Pediatric Gastroenterology and Nutrition, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2007, cilt 45, ss 366-369
DOI: 10.1097/mpg.0b013e31806907e8
Özet
OBJECTIVES: Because clinically evident manifestations are frequent in adults with celiac disease (CD), we aimed to investigate whether early neurological abnormalities may be detected in children with CD. METHODS: Electroencephalography, electromyography, and somatosensory evoked potentials were performed in children with CD receiving a gluten-free diet. RESULTS: The neurophysiological tests revealed subclinical neurological abnormalities associated with CD in 3 (11%) of 27 children: 2 had peripheral polyneuropathy documented with electromyography, and 1 had prolonged latencies in somatosensory evoked potential. Magnetic resonance imaging showed abnormalities in 2 (7.4%) of children: pontine demyelinization in 1 and cortical atrophy in the other. CONCLUSIONS: Because the rate of neurological problems is increased in children with CD, neurological abnormalities should be carefully investigated early after the diagnosis of CD is made.