Liver biopsy interpretation for causes of late liver allograft dysfunction
Makaleler > Tam Makale · 2006
Yazarlar: Anthony J. Demetris, Oyedele Adeyi, Chris O. C. Bellamy, Andrew Clouston, Frederic Charlotte, Albert Czaja, Ierachmiel Daskal, Magda S. El-Monayeri, Paulo Fontes, John Fung, Bruno Gridelli, Maria Guido, Hironori Haga, John Hart, Eva Honsova, Stefan Hubscher, Tomoo Itoh, Nirag Jhala, Patricia Jungmann, Urmila Khettry, Charles Lassman, Saverio Ligato, John G. Lunz, Amadeo Marcos, Marta Ida Minervini, Johan Moelne, Mike Nalesnik, Imad Nasser, Desley Neil, Erin Ochoa, Orit Pappo, Parmjeet Randhawa, Finn P. Reinholt, Phil Ruiz, Mylene Sebagh, Marco Spada, Aurelio Sonzogni, Athanassios C. Tsamandas, Annika Wernerson, Tong Wu, Funda YILMAZ BARBET
HEPATOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2006, cilt 44, ss 489-501
DOI: 10.1002/hep.21280
Özet
Evaluation of needle biopsies and extensive clinicopathological correlation play an important role in the determination of liver allograft dysfunction occurring more than I year after transplantation. Interpretation of these biopsies can be quite difficult because of the high incidence of recurrent diseases that show histopathological, clinical, and serological features that overlap with each other and with rejection. Also, more than one insult can contribute to allograft injury. In an attempt to enable centers to compare and pool results, improve therapy, and better understand pathophysiological disease mechanisms, the Banff Working Group on Liver Allograft Pathology herein proposes a set of consensus criteria for the most common and problematic causes of late liver allograft dysfunction, including late-onset acute and chronic rejection, recurrent and new-onset viral and autoimmune hepatitis, biliary strictures, and recurrent primary biliary cirrhosis and primary sclerosing cholangitis. A discussion of differential diagnosis is also presented.