A comparative evaluation of coenzyme Q10-loaded liposomes and solid lipid nanoparticles as dermal antioxidant carriers
Makaleler > Tam Makale · 2012
Yazarlar: Evren Homan GÖKÇE, Emrah KORKMAZ, Sakine TUNCAY TANRIVERDİ, Eleonora Dellera, Giuseppina Sandri, M. Cristina Bonferoni, Kevser Özgen ÖZER
INTERNATIONAL JOURNAL OF NANOMEDICINE, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2012, cilt 7, ss 5109-5109
DOI: 10.2147/ijn.s34921
Özet
Background: The effective delivery of coenzyme Q10 (Q10) to the skin has several benefits in therapy for different skin pathologies. However, the delivery of Q10 to deeper layers of skin is challenging due to low aqueous solubility of Q10. Liposomes and solid lipid nanoparticles (SLN) have many advantages to accomplish the requirements in topical drug delivery. This study aims to evaluate the influence of these nanosystems on the effective delivery of Q10 into the skin.