CAN N-ACETYLCYSTEINE PRESERVE PERITONEAL FUNCTION AND MORPHOLOGY IN ENCAPSULATING PERITONEAL SCLEROSIS?
Articles > Article · 2009
Authors: Devrim BOZKURT, Ender HUR, Burcu ULKUDEN, Murat SEZAK, Hasim NAR, Ozlem PURCLUTEPE, Sait ŞEN, Soner DUMAN
PERITONEAL DIALYSIS INTERNATIONAL, Journal Indexed in SCI Expanded, International, 2009, vol 29
Summary
Long-term use of the peritoneum as a dialysis membrane results in progressive irreversible dysfunction, described as peritoneal fibrosis. Oxidative stress during peritoneal dialysis has been established in many studies. Generation of reactive oxygen species (ROS) by conventional peritoneal dialysis solutions, regardless of whether produced by high glucose, angiotensin II, or glucose degradation products may be responsible for progressive membrane dysfunction.