Evaluation of a direct fluorescent antibody test for detection of Chlamydia trachomatis in endocervical specimens

Articles > Article · 1991

Authors: DENIZ Dereli, EKIN Ertem, DEMIR Serter, KEMAL YÜCe

APMIS, International, 1991, vol 99, pp 961-964

DOI: 10.1111/j.1699-0463.1991.tb01284.x

Summary

A total of 160 endocervical specimens collected from 72 symptomatic and 82 asymptomatic women attending a gynecology outpatient clinic were investigated for genital Chlamydia trachomatis infection by the use of tissue culture and DFA test. The infection rate was 42% for symptomatic and 23% for asymptomatic patient groups. The sensitivity rates of the DFA test in the symptomatic and asymptomatic groups were 84% and 75%), while the specificity rates were 89% and 95%, respectively. The DFA test had an overall sensitivity of 80% and specificity of 93%. There was 90% agreement between the two techniques. Therefore, DFA is recommended as an alternative to tissue culture where laboratory facilities are limited and genital chlamydial infections are highly prevalent.

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