SYNTHESIS OF MEMBRANE STRUCTURES CONTAINING NANOCOMPOSITES FOR IMMUNOGLOBULIN G (IgG) ADSORPTION

Makaleler > Tam Makale · 2024

Yazarlar: Özçelik, Hilal, Subaşı, Yasemin, Kibaroğlu, Mirza, Yaşar, Esra, Güner, Timuçin, Tiktaş, Kaan, Sinan AKGÖL

Anadolu Farmasötik Bilimler Dergisi, Uluslararası, 2024

Özet

The discovery of markers of many diseases, such as cancer, inflammation, diabetes, cardiovascular diseases and other autoimmune diseases, can be made through the characterization of serum protein or peptide. Proteomics, the large-scale analysis of proteins, will make a major contribution to our understanding of gene function in the post-genomic era. Proteomics is the quantitative and physical mapping of total proteins in a particular cell line, tissue, body fluids, or organism.In our study, it is aimed to adsorption of antibodies from solutions Accordingly, GO-HEMA membranes were synthesized by photopolymerization method, followed by scanning electron microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). During IgG binding to GO-HEMA membranes, pH, temperature, concentration and time parameters were examined.

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