The inorganic pyrophosphatase activity of erythrocytes in favism
Articles > Article · 1961
Authors: Güngör Ernişli, Faolo Brunetti
The Turkish Journal of Pediatrics, International, 1961, vol 3, pp 193-200
DOI: 10.24953/turkjpediatr.1961.9314
Summary
Inorganic pyrophosphatase activity of erythrocytes was found to be decreased in subjects affected by the glucose-6-phosphate dehydrogenase deficiency.During the acute hemolytic episode of favism, pyrophosphatase activity shows a further critical fall.Pyrophosphatase from glucose-6-phosphate dehydrogenase deficient erythrocytes is easily inactivated when RBC are incubated with proper amounts of acetylphenylhydrazine; such instability can be used for the detection of the glucose-6-phosphate dehydrogenase deficiency.