393eP A viral footprint in tumor immunity: Anti-HBc IgG serostatus as a prognostic marker in melanoma
Articles > Article · 2025
Authors: A. Gecgel, O. Özkan, D. Gunenc, B. Süllü, B. Arslan Bayir, I. Ozsavas, I. Ozdemir, T. Yamazhan, M. Tasbakan, S.B. Karaca Yayla
Immuno-Oncology and Technology, International, Scopus, 2025, vol 28, pp 101571-101571
DOI: 10.1016/j.iotech.2025.101571
Summary
Prior HBV exposure can induce immune imprinting that shapes future immune responses, including antitumor immunity. We investigated whether anti-HBc IgG seropositivity, a marker of past HBV exposure, predicts improved efficacy of immune checkpoint inhibitors (ICIs) in metastatic melanoma.