393eP A viral footprint in tumor immunity: Anti-HBc IgG serostatus as a prognostic marker in melanoma

Makaleler > Tam Makale · 2025

Yazarlar: A. Gecgel, O. Özkan, D. Gunenc, B. Süllü, B. Arslan Bayir, I. Ozsavas, I. Ozdemir, T. Yamazhan, M. Tasbakan, S.B. Karaca Yayla

Immuno-Oncology and Technology, Uluslararası, Scopus, 2025, cilt 28, ss 101571-101571

DOI: 10.1016/j.iotech.2025.101571

Özet

Prior HBV exposure can induce immune imprinting that shapes future immune responses, including antitumor immunity. We investigated whether anti-HBc IgG seropositivity, a marker of past HBV exposure, predicts improved efficacy of immune checkpoint inhibitors (ICIs) in metastatic melanoma.

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