Determining Toxoplasma high-risk autologous and allogeneic hematopoietic stem cell transplantation patients by systematic pre-transplant PCR screening of stem cell originated buffy coat
Articles > Article · 2012
Authors: Ayşe CANER, Ayhan DÖNMEZ, Mert DÖŞKAYA, Aysu DEĞİRMENCİ DÖŞKAYA, Murat TOMBULOĞLU, Seckin Cagırgan, Edward Guy, Janet Francıs, Nur SOYER, Adnan Yüksel GÜRÜZ
PARASITOLOGY INTERNATIONAL, Journal Indexed in SCI Expanded, International, 2012, vol 61, pp 565-571
DOI: 10.1016/j.parint.2012.05.005
Summary
The diagnosis of Toxoplasma infection or disease in hematopoietic stem cell transplantation (HSCT) patients is achieved mainly by PCR screening; however screening did not find wide field of use in practice due to costly expenditures of PCR. This study aimed to determine patients at high risk of Toxoplasma infection or disease before transplantation by stem cell originated buffy coat PCR and subsequently to screen them.