Determining Toxoplasma high-risk autologous and allogeneic hematopoietic stem cell transplantation patients by systematic pre-transplant PCR screening of stem cell originated buffy coat
Makaleler > Tam Makale · 2012
Yazarlar: Ayşe CANER, Ayhan DÖNMEZ, Mert DÖŞKAYA, Aysu DEĞİRMENCİ DÖŞKAYA, Murat TOMBULOĞLU, Seckin Cagırgan, Edward Guy, Janet Francıs, Nur SOYER, Adnan Yüksel GÜRÜZ
PARASITOLOGY INTERNATIONAL, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2012, cilt 61, ss 565-571
DOI: 10.1016/j.parint.2012.05.005
Özet
The diagnosis of Toxoplasma infection or disease in hematopoietic stem cell transplantation (HSCT) patients is achieved mainly by PCR screening; however screening did not find wide field of use in practice due to costly expenditures of PCR. This study aimed to determine patients at high risk of Toxoplasma infection or disease before transplantation by stem cell originated buffy coat PCR and subsequently to screen them.