Constituents of Pterocephalus pinardii Boiss
Makaleler > Tam Makale · 2009
Yazarlar: Derya GÜLCEMAL, E Bedir, Tamer KARAYILDIRIM, M Milena, S Piacente, SG Şenol, Özgen ALANKUŞ
Planta Medica, Uluslararası, Wos, 2009, cilt 75
Özet
In this study, we have examined chemical constituents of the above-ground parts of Pterocephalus pinardii Boiss. which is an endemic plant belonging to the family Dipsacaceae. Hydroxycinnamic acid esters, iridoids, phenolic glucosides, lignans [1], triterpenoid saponins [2,3] and flavonoid C-glycosides [4] were isolated from the genus Pterocephalus previously. This is the first phytochemical investigation on Pterocephalus pinardii . The MeOH extract of the plant material was suspended in H 2 O, and then partitioned in turn with CH 2 Cl 2 and n -BuOH. Butanolic extract was fractionated over VLC (RP-18). The fractions repeatedly subjected to normal phase silica gel CC and MPLC (RP-18) and four compounds were isolated ( 1–4 ). Structures of 1–3 were determined as α-morroniside, β-morroniside and oxayohimban-5-carboxylic acid, respectively, by using spectral methods. Oxayohimban-5-carboxylic acid ( 3 ) is reported for the second time from nature. References: [1] Graikou, K. et al. (2006) Biochem. Syst. Ecol. 34:438–441. [2] Tian, J. et al. (1993) Phytochemistry 32:1535–1538. [3] Tian, J. et al. (1993) Phytochemistry 32:1539–1542. [4] Ahmed, F.A., Shahat A.A. (2006) Nat. Prod. Comm. 1:457–459.