Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis
Makaleler > Tam Makale · 2018
Yazarlar: L Ortiz-Fernández, Fd Carmona, R López-Mejías, Mf González-Escrıbano, Pa Lyons, Aw Morgan, Ah Sawalha, Kgc Smıth, Ma González-Gay, Kenan AKSU, Gökhan KESER
ANNALS OF THE RHEUMATIC DISEASES, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2018, cilt 77, ss 589-595
DOI: 10.1136/annrheumdis-2017-212372
Özet
Objetive Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we performed the first cross-phenotype meta-analysis of genetic data from different clinically distinct patterns of vasculitis.