Triterpene saponins from the roots of Acacia albida Del. (Mimosaceae)

Articles > Article · 2016

Authors: Abdou TCHOUKOUA, Turibio Kuiate Tabopda, Shota Uesugi, Misa OHNO, Ken-ichi KİMURA, Eunsang Kwon, Hiroyuki Momma, Ibrahim Horo, Özgen ALANKUŞ, Yoshihito SHİONO, Bonaventure Tchaleu NGADJUİ

Phytochemistry, Journal Indexed in SCI Expanded, International, WoS, 2016, vol 136, pp 31-38

DOI: 10.1016/j.phytochem.2016.12.019

Summary

Seven previously undescribed bidesmosidic triterpenoid saponins named albidosides A - G, were isolated from a methanol extract of the roots of Acacia albida. Their structures were elucidated using 1D and 2D NMR spectroscopy and mass spectrometry and determined to be bidesmosides of oleanolic acid and of 16 alpha-hydroxyoleanolic acid. Albidosides B - G were assayed for their cytotoxicity against HeLa and HL60 cells using MTT method and microscopic observation. (C) 2016 Elsevier Ltd. All rights reserved.

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