Investigation of the presence of carbapenemases in carbapenem-resistant Klebsiella pneumoniae strains by MALDI-TOF MS (matrix-assisted laser desorption ionization-time of flight mass spectrometry) and comparison with real-time PCR method
Articles > Article · 2021
Authors: Yas Comma Ar-Duman Melike, Fatma Feriha ÇİLLİ
INDIAN JOURNAL OF MEDICAL MICROBIOLOGY, Journal Indexed in SCI Expanded, International, 2021, vol 39, pp 300-305
DOI: 10.1016/j.ijmmb.2021.03.013
Summary
Purpose: We aimed to develop a new procedure for rapid detection of the carbapenemase activity using MALDI-TOF MS, and to determine the sensitivity and specificity of the method. Also, we aimed to determine the distribution of carbapenemase genes among the K.pneumoniae strains isolated in our hospital using real-time PCR.