Matrix metalloproteinase-2,-9, and-12 gene polymorphisms in generalized aggressive periodontitis
Makaleler > Tam Makale · 2007
Yazarlar: Ali GÜRKAN, Gülnur EMİNGİL, Buket Han SAYGAN, FATMA GÜL ATİLLA, SERHAT ÇINARCIK, Timur KOESE, Afig BERDELİ
JOURNAL OF PERIODONTOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2007, cilt 78, ss 2338-2347
Özet
Background: Matrix metalloproteinases (MMPs) are involved in periodontal tissue remodeling and degradation. Polymorphisms in the promoter region of the MMP-2 and -9 genes and in the coding region of the MMP-12 gene could affect transcription and the function of these enzymes. The aim of the present study was to determine the association between the aforementioned MMP polymorphisms and generalized aggressive periodontitis (GAgP).