The landscape and trajectory of global CRISPR therapeutics

Articles > Article · 2026

Authors: Ceren Şahin, Teresa Maria Formica, Alfredo Silva, Giulia Della Pelle, Maria C. Davis, Daniel Gottenborg Andersen, Mısra Çavdar, Lúcia Santos, Liyan Qiu, Amalie Lykke Olsen, Anne Louise Askou, Mariana Köber, Cecilia Jimenez-Mallebrera, Marina Cortijo Gutiérrez, Johannes Frasez Soerensen, Francisco Martín, Rasmus O. Bak, Aylin ŞENDEMİR, Paula Río, Alessia Cavazza, Karim Benabdellah, Rajeevkumar Raveendran Nair, Yonglun Luo

Molecular Therapy Nucleic Acids, International, WoS, 2026, vol 37, pp 103011-103011

DOI: 10.1016/j.omtn.2026.103011

Summary

(GenE-HumDi) provide a comprehensive global overview of the CRISPR therapeutic landscape. We systematically analyze CRISPR-based therapeutic trials registered on ClinicalTrials.gov and the EU Clinical Trials Register, providing a thorough assessment of the current clinical activity and the trajectory of CRISPR technology as it advances toward routine clinical interventions.

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