The Relationship between Melatonin and Cannabinoid-1 Receptor in Cortical Dysplasia Generated Rats
Articles > Article · 2014
Authors: Esra ERDOGAN, Yiğit UYANIKGİL, Emin OZTAS
JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, Journal Indexed in SCI Expanded, International, 2014, vol 31, pp 346-354
Summary
Objectives: Cortical dysplasia is a developmental malformation that occurs as a result of defects in neuronal proliferation, migration and organization during the formation of brain cortex layers. Cannabinoid-1 Receptor (CB1R) plays a role in brain cortex development. Melatonin neuroprotective is an agent. In this study using an experimental cortical dysplasia model, CB1R expression and the effect of melatonin on CB1R were investigated.