The Relationship between Melatonin and Cannabinoid-1 Receptor in Cortical Dysplasia Generated Rats
Makaleler > Tam Makale · 2014
Yazarlar: Esra ERDOGAN, Yiğit UYANIKGİL, Emin OZTAS
JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2014, cilt 31, ss 346-354
Özet
Objectives: Cortical dysplasia is a developmental malformation that occurs as a result of defects in neuronal proliferation, migration and organization during the formation of brain cortex layers. Cannabinoid-1 Receptor (CB1R) plays a role in brain cortex development. Melatonin neuroprotective is an agent. In this study using an experimental cortical dysplasia model, CB1R expression and the effect of melatonin on CB1R were investigated.