Management of Primary Immune Thrombocytopenia – Turkish Modified Delphi-Based Consensus Statement for Special Considerations
Makaleler > Tam Makale · 2024
Yazarlar: Elif Gulsum Umit, Ahmet Muzaffer Demir, Muhlis Cem Ar, Mesut Ayer, Meltem Ayli, Volkan Karakus, Emin Kaya, Fahir Ozkalemkas, Nilgun Sayinalp, Mehmet Sonmez, Fahri ŞAHİN, Selami Kocak Toprak, Tayfur Toptas, Irfan Yavasoglu, Umran Calis
Turkish Journal of Hematology, SCI İndekslerine Giren Dergi, Uluslararası, Wos, 2024, cilt 41, ss 141-145
DOI: 10.4274/tjh.galenos.2024.2024.0101
Özet
Objective: Primary immune thrombocytopenia (ITP) is an acquired disorder of platelets with a complex and unclear mechanism of increased immune destruction or impaired production of platelets. While the management of ITP is evolving, there is still a need for guidance, particularly in certain circumstances such as pregnancy, emergencies, or patients requiring co-medications. We aimed to determine the tendencies of hematologists in Türkiye in the event of such special considerations. Materials and Methods: Applying a modified Delphi method, the Turkish National ITP Working Group, founded under the auspices of the Turkish Society of Hematology, developed a questionnaire consisting of statements regarding pregnancy, emergencies, and circumstances requiring co-treatment with antiaggregants or anticoagulants. A total of 107 hematologists working in university or state hospitals voted for their agreement or disagreement with the statements for two sequential rounds. Results: /L were regarded as safe for low-risk procedures as well as co-treatment with antiplatelets or anticoagulants. Conclusion: As the National ITP Study Group, we have observed the need to increase the practice guidance regarding patients with primary ITP requiring additional treatments including invasive interventions and co-treatments for coagulation. Decisions on the management of ITP during pregnancy should be individualized. There is a lack of consensus on the thresholds of platelet counts as well as co-morbidities and co-medications. This lack of consensus may be due to variations in practices.