Primary diffuse large B-cell lymphoma of the lacrimal sac simulating chronic dacryocystitis
Makaleler > Tam Makale · 2011
Yazarlar: Melis PALAMAR ONAY, Rasit MIDILLI, Nazan ÖZSAN, SAİT EĞRİLMEZ, Fahri ŞAHİN, AYŞE YAĞCI
Auris Nasus Larynx, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2011, cilt 38, ss 643-645
DOI: 10.1016/j.anl.2011.01.012
Özet
Primary diffuse large B-cell lymphoma of the lacrimal sac is rare. Herein we report a 55-year-old female presented with epiphora in the right eye. Distention of the lacrimal sac secondary to nasolacrimal duct obstruction was observed. She was scheduled for external dacryocystorinostomy for the next month. When she came for surgery, a growing mass was recognised over the lacrimal sac region. On computer tomography scan, a subdermal mass causing nasal bone destruction was detected. Excisional biopsy of the mass was performed. Histopathologic and immunohistochemical evaluations revealed primary diffuse large B-cell non-Hodgkin lymphoma of the lacrimal sac. She was treated with cyclophospamide, vincristine, adriablastine and prednisone for eight courses combined with rituximab for 6 months. During a follow-up period of 25 months, patient is stable with no systemic disease. Although rare, lacrimal sac tumors can mimic dacryocystitis and must be considered in differential diagnosis. In suspicious cases incisional biopsy is recommended. (c) 2011 Elsevier Ireland Ltd. All rights reserved.