A cross-sectional, mono-centric pilot study of insulin resistance in enzyme replacement therapy patients with Gaucher type I without overweight
Articles > Article · 2009
Authors: Sema KALKAN UÇAR, Mahmut ÇOKER, MEHMET ARGIN, Sezin Akman, sinan KARA, Ruhsar Damla GÖKŞEN, Şükran DARCAN
MOLECULAR GENETICS AND METABOLISM, Journal Indexed in SCI Expanded, International, 2009, vol 96, pp 50-51
DOI: 10.1016/j.ymgme.2008.10.001
Summary
Insulin resistance have been demonstrated in untreated patients with Gaucher type I disease. It was implied in overweight enzyme replacement therapy (ERT) treated patients with Gaucher type I disease. In present study we investigate whether insulin resistance is presented in fourteen ERT treated patients with Gaucher type I disease and without overweight in comparison to normal subjects. This work illustrates the presence of insulin resistance in non-overweight ERT treated patients with Gaucher type I disease. (C) 2008 Elsevier Inc. All rights reserved.