Metheboglobinemia Developing in Four Infants after Local Anesthesia
Articles > Article · 2015
Authors: Ali YURTSEVEN, Eylem Ulaş SAZ
JOURNAL OF PEDIATRIC RESEARCH, Journal Indexed in SCI Expanded, International, 2015, vol 2, pp 223-226
DOI: 10.4274/jpr.07708
Summary
Methemoglobinemia (MH) is defined as blood methemoglobin (Met-Hb) concentration > 1%. Met-Hb is an abnormal form of hemoglobin in which iron is oxidized from the ferrous (Fe2+) to the ferric state (Fe3+). Since Met-Hb cannot bind and transport oxygen, increased levels of Met-Hb are associated with clinically severe symptoms. In this study, we presented 4 cases of MH, developed after the administration of prilocaine prior to the circumcision procedure.