A case of juvenile pityriasis rubra pilaris: could varicella be an aetiological agent?
Makaleler > Tam Makale · 2009
Yazarlar: İlgen ERTAM SAĞDUYU, A. O. Sezgin, A. Kazandi, T. Dereli, İdil ÜNAL
Clinical and Experimental Dermatology, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2009, cilt 34, ss e1012-e1013
DOI: 10.1111/j.1365-2230.2009.03678.x
Özet
Conflict of interest: none declared. Pityriasis rubra pilaris (PRP) is characterized by follicular erythematous papules and diffuse erythematous plaques with pityriasiform scale. However, the precise aetiology is not known; genetic factors, human immunodeficiency virus (HIV) and other infections are thought to be involved.1 A 7‐year‐old girl was admitted to our clinic with a 10‐day history of fever and erythematous and squamous lesions on the face, trunk and limbs. The child had been diagnosed with varicella infection 10 days before the development of these lesions. On physical examination, bilateral ectropion, erythema and oedema on the face, and diffuse follicular erythematous papules on the trunk and limbs were seen (Fig. 1a). There were also a few crusted varicella lesions on the arms. The oropharynx and tonsils were hyperaemic. Histological examination of a skin biopsy found superficial thick orthokeratosis, parakeratotic shoulders and expansion of the follicle pores on the keratinous layer, keratin plugs, and epithelial irregular psoriasiform hyperplasia. Chest X‐ray was normal. A full blood count revealed leucocytosis and thrombocytosis. Liver and renal function tests were normal. Blood, urine and oropharyngeal cultures were negative. Serology for Epstein–Barr, cytomegalovirus, rubella and parvovirus‐B19 was negative.