Childhood Intraosseous Myofibroma: A Case Report and Review of the Literature
Makaleler > Tam Makale · 2025
Yazarlar: Betül ALPAGUTER, Gözde IŞIK, İlhan UZEL, Meltem ÖZDEN YÜCE
INTERNATIONAL ARCHIVES OF DENTAL SCIENCES, Hakemli Üniversite Dergisi, Uluslararası, Ebsco, 2025, cilt 46, ss 159-164
Özet
Myofibroma, a rare benign tumor, frequently occurs in the head and neck regions, particularly the tongue, gingivae, maxillary, and mandible, often involving the bone.This tumor comprises highly proliferative spindle cells, including fibroblasts and myoblasts, and often presents with lytic radiographic areas and painless masses.Treatment varies from conservative management to radical resection, depending on patient age, tumor location, and severity.This report details a rare case of mandibular myofibroma with bony involvement in a 6-year-old girl, highlighting its diagnosis and treatment.The patient presented with a painless, smooth red mass in the right lower jaw, impairing chewing and causing bleeding.Clinical and radiological evaluations revealed a fixed mass between the right primary canine and permanent first molar, with radiolucent features on panoramic radiography.An excisional biopsy under general anesthesia was performed, leading to the removal of the lesion and the first molar.Histopathological examination identified spindle cells with myofibroblastic differentiation, and immunohistochemical staining showed a high proliferative rate of Ki67.Followup over two years showed no recurrence, and soft tissue healing was satisfactory.This case emphasizes the importance of conservative management and thorough follow-up in treating pediatric myofibroma with bony involvement, avoiding radical procedures where possible.