N‐functionalized azolin‐2‐ylidene‐palladium‐catalyzed heck reaction
Makaleler > Tam Makale · 2008
Yazarlar: Ismail Özdemir, Nevin Gürbüz, Yetkin Gök, Bekir Çetinkaya
Heteroatom Chemistry, Uluslararası, 2008, cilt 19, ss 82-86
DOI: 10.1002/hc.20415
Özet
Abstract Novel 1,3‐dialkylimidazolidinium, 1,3‐dialkyl‐3,4,5,6‐tetrahydropyrimidinium, and 1,3‐dialkyl‐1H‐4,5,6,7‐tetrahydrodiazepinium hexafluorophosphates (1a–c, 2a–c) as N‐heterocyclic carbene precursors have been synthesized and characterized. The incorporation of saturated N‐heterocyclic carbenes into palladium precatalysts gives high‐catalyst activity in the Heck coupling of aryl bromide substrates in aqueous media. The complexes were generated in the presence of Pd(OAc)2 by in situ deprotonation of 1,3‐dialkylazolinium salts 1, 2. © 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:82–86, 2008; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/hc.20415